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Multivariable analysis of PIK3CA mutation associated with disease-free survival, Cox regression model adjusted for p16 overexpression, alcohol/tobacco consumption habits, and age at diagnosis.
| Adjusted HR * | 95% CI | p-Value | |
|---|---|---|---|
| HPV status positive | |||
| PIK3CA | |||
| Mutated | 1 | ||
| Wild-type | 4.64 | 1.02–20.99 | 0.047 |
| HPV not detected | |||
| PIK3CA | |||
| Mutated | 1 | ||
| Wild-type | 0.38 | 0.06–2.24 | 0.285 |
* Hazard ratio adjusted for p16 overexpression, consumption habits, and age at diagnosis.
