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. 2022 Feb 26;14(5):1217. doi: 10.3390/cancers14051217

Table 1.

Table shows CT26 tumour retention of [18F]AlF-NOTA-KCNA3P in vivo after ICI treatment evaluated by PET/CT. Data are shown as the mean %ID/g ± S.D. of control groups, treatment responsive tumours (TR) across treatment cohorts and treatment non-responders (TNR) (n = 10 mice/ group; * p < 0.05; ** p < 0.01, comparing TR to TNR).

Treatment Group [18F]AlF-NOTA-KCNA3P Tumour Uptake
(%ID/g ± SD)
Control 0.51 ± 0.19
Treatment Responsive tumours (TR)
αPD1
0.87 ± 0.15 *
αPD1 + αCTLA4 1.30 ± 0.36 **
Treatment Non-Responders (TNR) 0.53 ± 0.20