FIGURE 2.

Dose-dependent microcapsule loading increases nitrite levels and cell activation. Cells were incubated with microcapsules at various ratios (1:0, 1:10, 1:20, and 1:45) and cultured for 24, 48, or 72 h post-phagocytosis; at the indicated time points, the supernatant media were collected and analyzed for nitrite content via cyclic voltammetry. Each sample was measured 3–5 times, n = 3 per each conditions and time points. *р < .05 versus the corresponding cell/microcapsule ratio at 24 h post phagocytosis; ^# p < .05 versus control at the same time point.