Table 1.
Clinical parameters of control and PCOS subjects (mean ± standard deviation).
| Clinical Parameters | Control Subjects (n = 13) |
PCOS Subjects (n = 6) |
p-Value |
|---|---|---|---|
| Age (years) | 34 ± 5.6 | 26 ± 2.7 | 0.008 |
| Race (C/H/AA/other) | 8/2/2/1 | 4/2/0/0 | |
| Adiposity markers | |||
| BMI (kg/m²) | 34.5 ± 2.7 | 34.8 ± 3.1 | 0.95 |
| Weight (kg) | 96 ± 9.3 | 92 ± 6.1 | 0.41 |
| Hip circumference | 114.9 ± 7.19 | 116.9 ± 6.40 | 0.76 |
| Waist circumference | 107.1 ± 5.56 | 104.3 ± 2.92 | 0.25 |
| Waist to hip ratio | 0.93 ± 0.04 | 0.89 ± 0.04 | 0.15 |
| Total fat mass (kg) | 42.2 ± 6.91 | 44.5 ± 6.60 | 0.70 |
| Total lean mass (kg) | 52.1 ± 4.20 | 47.5 ± 3.94 | 0.05 |
| Fat mass (%) | 44 ± 3.7 | 48 ± 4.4 | 0.12 |
| Lean mass (%) | 54 ± 3.5 | 51 ± 3.8 | 0.13 |
| Visceral fat mass (kg) | 12.3 ± 4.33 | 10.4 ± 3.08 | 0.32 |
| Energy expenditure (kcal/day) | 2559 ± 300 | 2469 ± 304 | NS |
| Metabolic markers | |||
| Fasting glucose (mg/dL) | 93.2 ± 11.6 | 85.8 ± 5.92 | NS |
| Fasting insulin (mU/L) | 5.49 ± 3.09 | 4.14 ± 1.74 | NS |
| QUICKI | 0.38 ± 0.05 | 0.39 ± 0.04 | NS |
| FFA (mmol/L) | 0.41 ± 0.09 | 0.51 ± 0.12 | NS |
| Circulating Hormones | |||
| TSH (mU/L) | 1.78 ± 0.65 | 1.33 ± 0.81 | NS |
| Total testosterone (ng/dL) | 25.6 ± 17.6 | 63.2 ± 25.1 | 0.007 |
| SHBG (nmol/L) | 35.4 ± 21.1 | 51.8 ± 49.2 | NS |
| Free testosterone (ng/dL) | 0.46 ± 0.40 | 1.24 ± 0.91 | 0.05 |
| Bioavailable testosterone (ng/dL) | 11.5 ± 10.1 | 30.0 ± 22.4 | 0.05 |
NS = not significant.