TABLE 1.

Demographic and clinical data of patients (n=29)

Gender	16 men (56.6%) 13 women (43.4%)
Age (year)	14±3.8
Age at first attack (year)	6.7±4.11
Age at the time of diagnosis (year)	8.2±4.31
Diagnosis lag time (year)	1 (0–9)
Indication for switch from CD to CO	Intolerance: 11 (37.93%)
	Nonresponsiveness: 18 (62.07%)
Genetically assessment	M694V (+/+): n= 9 (% 62)
	M694V (+/−): n=3 (% 10.3)
	M694V/M680I/R202Q: n=1 (3.4%)
	M680I/V726A: n=1 (3.4%)
	M694V/R202Q: n=1 (3.4%)
	M680I/R202Q: n=1 (3.4%)
	V726A/E167D/F479L: n=1 (3.4%)
	E148Q/R202Q: n=1 (3.4%) *
	R202Q (+/−): n=1 (3.4%) *

^*These patients were further searched for mutations on MVK, TNFRF1A, and NLRP3 genes and showed no mutations and they were diagnosed as having FMF owing to typical clinical findings as defined in the Ankara criteria