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. 2022 Feb 27;14(5):1236. doi: 10.3390/cancers14051236
Arg-1 arginase 1
CSFs colony-stimulating factors
CCL2 C-C motif chemokine ligand 2
CCL5 C-C motif ligand 5
CCR2 C-C chemokine receptor type 2
CXCR2 C-X-C motif chemokine receptor 2
EMT epithelial–mesenchymal transition
G-CSF granulocyte colony-stimulating factor
GM-CSF granulocyte/macrophage colony-stimulating factor
HIF1α hypoxia-inducible factor 1-alpha
HGF hepatocyte growth factor
IL-1β interleukin-1beta
IL-6 interleukin-6
iNOS inducible NO synthase
IFN-I type I interferons
IL-4Rα interleukin-4 receptor alpha
MDSCs myeloid-derived suppressor cells
M-MDSCs monocytic MDSCs
M-CSF macrophage colony-stimulating factor
MMP matrix metalloproteinase
Nox2 NADPH oxidase
NO nitric oxide
Nos2 nitric oxide synthase 2
N1 tumor-suppressing neutrophils
N2 tumor-promoting neutrophils
NETs neutrophil extracellular traps
PMN-MDSCs polymorphonuclear MDSCs
PNT peroxynitrite
PDAC pancreatic ductal adenocarcinoma cell
PyMT polyoma Middle T
PGE2 prostaglandin E2
PDE5 phosphodiesterase type 5
TNFα tumor necrosis factor α
TME tumor microenvironment
TGFβ transforming growth factor beta
TAM tumor-associated macrophages
ROS reactive oxygen species
RTK receptor tyrosine kinases
STAT3 signal transducer and activator of transcription 3