Table 2.
Sensitivity Analyses | Overall Survival (HR, 95% CI) | Time to Tumor Progression (HR, 95% CI) |
---|---|---|
Pembrolizumab ≥ 2 mg/kg as standard group † |
0.84 (0.62–1.14) | 0.85 (0.68–1.05) |
Pembrolizumab ≥ 1.9 mg/kg as standard group † |
0.78 (0.58–1.03) | 0.85 (0.69–1.06) |
Pembrolizumab ≥ 1.8 mg/kg as standard group † |
0.73 (0.55–0.97) * | 0.81 (0.66–1.01) |
Propensity score matching cohort (pembrolizumab ≥2 mg/kg as standard group) | 0.83 (0.52–1.34) | 0.86 (0.61–1.20) |
Abbreviations—HR: hazard ratio, CI: confidence interval: Note: † adjusted by inverse probability of treatment weighting; * p < 0.05; Propensity score model covariates include: age, sex, Eastern Cooperative Oncology Group, alcohol habit, smoking habit, line of pembrolizumab, concomitant chemotherapy, Charlson comorbidity index, histologic features, metastasis status, programmed death-ligand 1 tumor proportion score and chronic diseases.