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. 2022 Feb 22;11(5):759. doi: 10.3390/cells11050759

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Analysis of the effect of endogenous AnxA1 knockout on HDM-induced cytokine and chemokine production in the lungs of mice. TGF-β (A), IL-4 (B), IL-13 (C), CCL11/eotaxin-1 (D), and CCL2/MCP-1 (E) were measured in lung tissue homogenates from saline- and HDM-challenged WT and ANXA1^−/− mice. Animals instilled with saline were used as controls. Analyses were performed 24 h after the last HDM or saline-challenged. Values represent the mean ± SEM from 6–7 animals per group. * p < 0.05 as compared to their respective saline-challenged groups; ^# p < 0.05 as compared to HDM-challenged WT group.