Figure 6.

Intranasal peptide Ac2-26 reduces leukocyte recruitment into the airways after HDM challenge. (A) Leukocyte accumulation in the bronchoalveolar lavage (BAL) and (B) peribronchiolar eosinophil infiltration in the lung tissue of HDM-challenged mice and treated with peptide Ac2-26 (200 µg/mouse, i.n.). Animals instilled with saline were used as controls. Quantitative assessments of eosinophil levels were performed in lung tissue as described in Section 2. Analyses were performed 24 h after the last HDM or saline challenge. Values represent the mean ± SEM from eight animals per group. * p < 0.05 as compared to the saline-challenged group; + p < 0.05 as compared to the HDM-challenged group.