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. 2022 Feb 22;11(5):759. doi: 10.3390/cells11050759

Figure 9.

Figure 9

Intranasal peptide Ac2-26 reduces proinflammatory cytokine and chemokine levels in the lung samples following HDM stimulation. Production of cytokines and of chemokine in the lungs of HDM-challenged mice and treated with peptide Ac2-26 (200 µg/mouse, i.n.). TGF-β (A), IL-4 (B), TNF-α (C), and CCL2/MCP-1 (D) were measured in lung tissue homogenates from saline- and HDM-challenged mice. Animals instilled with saline were used as controls. Analyses were performed 24 h after the last HDM or saline challenge. Values represent the mean ± SEM from eight animals per group. * p < 0.05 as compared to the saline-challenged group; + p < 0.05 as compared to the HDM-challenged group.