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ARBS interaction landscape. (a) Multiple ARBS reside in close proximity to AR-regulated genes. Frequency of ARBS were quantified using publicly available androgen-induced RNA-seq [182] and AR ChIP-seq [183] from LNCaP cells. (b) AR ChIA-PET cis-contacts are mostly concentrated around 10 kb to 1 mb. AR-mediated looping dataset were used calculate the frequency of chromatin loops in VCaP cells [169].
