Figure 3.

Proposed opportunity for advancement in synthetic hydrogel models of tumor vasculature. The vascular networks formed in synthetic hydrogels within microfluidic devices could enable the investigation of intravasation and extravasation. Tumor cells could be flowed through the vessels, allowing the live imaging of cells extravasating into the matrix. Alternatively, tumor cells could be incorporated into the matrix, allowing the live imaging of cells intravasating into the vascular network.