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. 2022 Mar 1;14(5):1279. doi: 10.3390/cancers14051279

Table 3.

Number of esophageal carcinoma patients with detectable expression of CK20 (CK20+) and DEFA5 (DEFA5+) in blood and bone marrow and their correlation with clinical parameters.

Variable CK20 + BL (%) p DEFA5 + BL (%) p CK20 + BM (%) p DEFA5 + BM (%) p
Gender Male 38 (21.5) 0.40 83 (46.9) 0.51 44 (34.6) 0.39 85 (66.9) 0.86
Female 9 (28.1) 13 (40.6) 5 (25) 13 (65)
Age [years] <70 32 (20.6) 0.28 72 (46.5) 0.79 34 (30.9) 0.28 74 (67.3) 0.79
>70 15 (27.8) 24 (44.4) 15 (40.5) 24 (64.9)
Histotype AC 35 (22.6) 0.78 70 (45.2) 0.71 39 (34.5) 0.50 78 (69) 0.25
SCC 12 (22.2) 26 (48.1) 10 (29.4) 20 (58.8)
pT category T1 12 (22.2) 0.81 29 (53.7) 0.30 12 (33.3) 0.54 23 (63.9) 0.24
T2 12 (25.5) 21 (44.7) 15 (39.5) 30 (78.9)
T3 19 (20.9) 38 (41.8) 18 (29) 37 (59.7)
T4 0 0 0 1 (50)
pN category N0 25 (24.8) 0.73 52 (51.5) 0.24 22 (31.4) 0.79 49 (70) 0.55
N1 13 (18.1) 32 (44.4) 19 (38) 32 (64)
N2 7 (25.9) 10 (37) 7 (31.8) 15 (68.2)
N3 2 (22.2) 2 (22.2) 1 (20) 2 (40)
pM category M0 45 (23.2) 0.38 88 (45.4) 0.55 47 (34.6) 0.27 91 (66.9) 0.82
M1 2 (13.3) 8 (53.3) 2 (18.2) 7 (63.6)
UICC stage I 11 (23.4) 0.91 27 (57.4) 0.30 11 (35.5) 0.91 21 (67.7) 0.79
II 10 (20) 21 (42) 12 (32.4) 26 (70.3)
III 18 (24) 31 (41.3) 18 (33.3) 35 (64.8)
IV 4 (18.2) 9 (40.9) 4 (25) 9 (56.3)
Neoadjuvant therapy Yes 21 (18.9) 0.19 53 (47.7) 0.57 25 (30.5) 0.41 57 (69.5) 0.41
No 26 (26.5) 43 (43.9) 24 (36.9) 41 (63.1)
Adjuvant
therapy
Yes 8 (14.8) 0.08 21 (38.9) 0.31 13 (31.7) 0.73 32 (78) 0.07
No 36 (26.9) 63 (47) 32 (34.8) 57 (62)

BL: blood, BM: bone marrow, AD: adenocarcinoma, SCC: squamous cell carcinoma, UICC: Union Internationale Contre le Cancer.