Table 1.

Characterization of the studies.

Author	Year	Population and Mean Age	Intervention	Control	Pharmacological Treatment	Scales Used	Results
Deguchi, N et al. [34]	2019	IG: 67 (67 years); CG: 52 (63.7 years)	Rehabilitation (same as the control group) + 6 PNE sessions were carried out by a physiotherapist, with each session lasting 60 min	Rehabilitation only (weight bearing as tolerated, 6 times a week in 40- to 60- minute sessions)	NSAIDs 3 times a day postoperatively, tapered off at 3 weeks postoperatively	NRS, PCS, PSEQ	No significant effects were found in the comparison items between groups, except catastrophizing.
Louw, A et al. [35]	2019	IG: 49 (74.1 ± 9.5) 31 analyzed; CG: 54 (69.6 ± 10.6) 36 analyzed	PNE	Traditional preoperative educational program	Opioid treatment according to the determined regulation	NRS, PCS, Tampa scale, WOMAC	No differences could be found between the groups.
Louw, A et al. [36]	2018	Patients = 12 [10 women + 2 men] (68.6 ± 8.7 years)	PNE	The second group was not managed	Not specified	NRS, PCS, Tampa Scale	There were changes in favor of the PNE group.
Lluch et al. [37]	2017	IG patients: 27 (72.8 ± 5.6); CG patients: 27 (67.7 ± 7.8)	PNE + knee joint mobilization	Biomedical education + Knee joint mobilization	Not specified	CSI, PCS, Tampa Scale, WOMAC	Changes were found regarding kinesiophobia and catastrophizing for PNE.

Abbreviations: IG (Intervention Group), CG (Control Group), PNE (pain neuroscience education), NSAIDs (non-steroidal anti-inflammatory drugs), (NRS (Numerical Rating Scale), PCS (Pain Catastrophizing Scale), PSEQ (Pain Self-Efficacy Questionnaire Score), Tampa (Scale of Kinesiophobia), WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index), CSI (Central Sensitization Inventory).