Table 2.

Multivariable Cox regression analysis of variables potentially associated with increased risk of tumor metastasis and tumor-specific survival in 54 dogs with non-metastatic appendicular osteosarcoma treated with amputation and chemotherapy.

Variable	Time to Metastasis	p	Tumor Specific Survival	p
Increased serum ALP activity	2.30 (0.92–5.72)	0.073	2.67 (1.05–6.76)	0.039 *
Lack of vaccine administration	2.25 (1.16–4.37)	0.017 *	2.75 (1.39–5.44)	0.004 *

* significant.