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. 2022 Feb 24;14(5):1169. doi: 10.3390/cancers14051169

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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A 70-year-old patient with biochemical recurrence after radical prostatectomy (Gleason 3 + 4 = 7, PSA-nadir < 0.1 ng/mL) with a PSA of 0.7 ng/mL at the PET/CT scan time. Restaging ¹⁸F-DCFPyL PET/CT detected multiple bone metastases (>10) at low serum PSA value ((A); maximum intensity projection). Transversal ¹⁸F-DCFPyL PET (B,E) and fused PET/CT (D,G) images illustrate two bone metastases (os pubis left, red arrow: SUV_max: 9.76; L5 vertebra, blue arrow SUV_max: 8.02) with sclerotic substrate on CT (C,F,H).