TABLE 1.

Comparative in vitro activities of different antibiotic compounds against MSSA in relation to ciprofloxacin susceptibility

Test agent	MIC (μg/ml)
	Ciprofloxacin-susceptible MSSA (n = 34)			Ciprofloxacin-resistant MSSA (n = 16)
	Range	MIC50	MIC90	Range	MIC50	MIC90
Ciprofloxacin	0.12–1	0.25	0.5	4–64	16	64
Clinafloxacin	≤0.06	≤0.06	≤0.06	≤0.06–2	0.5	1
Grepafloxacin	≤0.06–0.12	≤0.06	0.12	≤0.06–32	16	32
Levofloxacin	≤0.06–0.25	0.12	0.25	0.12–16	2	8
Moxifloxacin	≤0.06	≤0.06	≤0.06	≤0.06–2	0.5	1
Ofloxacin	0.12–1	0.25	0.5	1–32	8	16
Sparfloxacin	≤0.06–0.12	≤0.06	≤0.06	≤0.06–8	0.5	4
Trovafloxacin	≤0.06	≤0.06	≤0.06	≤0.06–2	0.5	1
Gentamicin	≤0.06–128	0.5	64	0.25–>256	64	>256
Linezolid	1–2	2	2	0.5–2	1	2
Quinupristin-dalfopristin	≤0.06–4	0.5	0.5	≤0.06–2	0.5	0.5
Vancomycin	0.5–2	1	1	0.5–2	1	2