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. 2022 Feb 28;14(5):1242. doi: 10.3390/cancers14051242

Table 2.

Details of Treatment Lines.

Lines (1–5) 1st Line 2nd Line 3rd Line 4th Line 5th Line Patients (n)
1 2-CdA 42
IFN-α 24
Splenectomy 7
2 2-CdA 2-CdA 8
2-CdA 2-CdA + R 1
IFN-α 2-CdA 11
IFN-α IFN-α 9
IFN-α Pentostatin 2
Splenectomy IFN-α 6
Splenectomy Chlorambucil 1
3 2-CdA 2-CdA 2-CdA + R 1
IFN-α 2-CdA 2-CdA 5
IFN-α IFN-α IFN-α 4
IFN-α IFN-α 2-CdA 3
Splenectomy IFN-α Pentostatin 3
Splenectomy IFN-α IFN-α 2
Splenectomy IFN-α 2-CdA 1
Splenectomy Chlorambucil IFN-α 1
4 IFN-α IFN-α IFN-α 2-CdA 2
IFN-α IFN-α IFN-α IFN-α 1
IFN-α IFN-α 2-CdA 2-CdA 1
IFN-α 2-CdA 2-CdA 2-CdA 1
Splenectomy IFN-α IFN-α Pentostatin 1
Splenectomy IFN-α Pentostatin Pentostatin 1
Splenectomy IFN-α Pentostatin IFN-α 1
Splenectomy Chlorambucil IFN-α Pentostatin 1
5 IFN-α IFN-α IFN-α IFN-α IFN-α 1
IFN-α IFN-α 2-CdA 2-CdA 2-CdA 1
IFN-α 2-CdA 2-CdA IFN-α 2-CdA 1
IFN-α 2-CdA 2-CdA IFN-α 2-CdA + R 1
Splenectomy IFN-α Pentostatin IFN-α 2-CdA 1

n, number; 2-CdA, cladribine; IFN-α, interferon-α, R, rituximab.