Table 2.
Lines (1–5) | 1st Line | 2nd Line | 3rd Line | 4th Line | 5th Line | Patients (n) |
---|---|---|---|---|---|---|
1 | 2-CdA | 42 | ||||
IFN-α | 24 | |||||
Splenectomy | 7 | |||||
2 | 2-CdA | 2-CdA | 8 | |||
2-CdA | 2-CdA + R | 1 | ||||
IFN-α | 2-CdA | 11 | ||||
IFN-α | IFN-α | 9 | ||||
IFN-α | Pentostatin | 2 | ||||
Splenectomy | IFN-α | 6 | ||||
Splenectomy | Chlorambucil | 1 | ||||
3 | 2-CdA | 2-CdA | 2-CdA + R | 1 | ||
IFN-α | 2-CdA | 2-CdA | 5 | |||
IFN-α | IFN-α | IFN-α | 4 | |||
IFN-α | IFN-α | 2-CdA | 3 | |||
Splenectomy | IFN-α | Pentostatin | 3 | |||
Splenectomy | IFN-α | IFN-α | 2 | |||
Splenectomy | IFN-α | 2-CdA | 1 | |||
Splenectomy | Chlorambucil | IFN-α | 1 | |||
4 | IFN-α | IFN-α | IFN-α | 2-CdA | 2 | |
IFN-α | IFN-α | IFN-α | IFN-α | 1 | ||
IFN-α | IFN-α | 2-CdA | 2-CdA | 1 | ||
IFN-α | 2-CdA | 2-CdA | 2-CdA | 1 | ||
Splenectomy | IFN-α | IFN-α | Pentostatin | 1 | ||
Splenectomy | IFN-α | Pentostatin | Pentostatin | 1 | ||
Splenectomy | IFN-α | Pentostatin | IFN-α | 1 | ||
Splenectomy | Chlorambucil | IFN-α | Pentostatin | 1 | ||
5 | IFN-α | IFN-α | IFN-α | IFN-α | IFN-α | 1 |
IFN-α | IFN-α | 2-CdA | 2-CdA | 2-CdA | 1 | |
IFN-α | 2-CdA | 2-CdA | IFN-α | 2-CdA | 1 | |
IFN-α | 2-CdA | 2-CdA | IFN-α | 2-CdA + R | 1 | |
Splenectomy | IFN-α | Pentostatin | IFN-α | 2-CdA | 1 |
n, number; 2-CdA, cladribine; IFN-α, interferon-α, R, rituximab.