Table 3.
Response after first and subsequent lines of treatment with IFN-α or purine analogues.
| Response | IFN-α | 2-CdA/Pentostatin | ||||
|---|---|---|---|---|---|---|
| 1st Line (n = 24) | 2nd Line (n = 15) | 3rd Line (n = 7) | 1st Line (n = 42) | 2nd Line (n = 20) | 3rd Line (n = 12) | |
| ORR (%) | 87.5 | 80.0 | 57.2 | 100 | 100 | 91.5 |
| CRu (%) | 20.8 | 13.3 | 14.3 | 85.7 | 90 | 41.5 |
| PR (%) | 66.7 | 66.7 | 42.9 | 14.3 | 10 | 50 |
| NR (%) | 12.5 | - | - | - | - | 8.3 |
IFN-α, interferon-α; 2-CdA, cladribine; Cru, undetermined complete remission; ORR, overall response rate; PR, partial remission; NR, no response.