TFs |
Transcription factors |
DBD |
DNA-binding domain |
TME |
Tumor microenvironment |
SRY |
Sex-determining region Y |
HMG |
High-mobility group |
SOX |
Sex-determining region Y-related high-mobility group box |
HCC |
Hepatocellular carcinoma |
TIME |
Tumor immune microenvironment |
CSCs |
Cancer stem cells |
TICs |
Tumor-initiating cells |
EMT |
Epithelial-mesenchymal transition |
miRNA |
MicroRNA |
HBV |
Hepatitis B virus |
SNP |
Single-nucleotide polymorphism |
3′UTR |
3′ untranslated region |
AFP |
Alpha-fetoprotein |
PVTT |
Portal vein tumor thrombosis |
HSCs |
Hepatic stellate cells |
MDSCs |
Myeloid-derived suppressor cells |
IFNI |
Type I interferon |
APCs |
Antigen-presenting cells |
DCs |
Dendritic cells |
STING |
Stimulator of interferon genes |
Treg |
Regulatory T cell |
ISG.RS |
Interferon-stimulated genes resistance signature |
ICIs |
Immune checkpoint inhibitors |
TANs |
Tumor-associated neutrophils |
TNBC |
Triple-negative breast cancer |
TAM |
Tumor-associated macrophage |
DCreg |
Regulatory dendritic cell |
Breg |
Regulatory B cell |
HLA |
Human leukocyte antigen |
SMO |
Smoothened |
PROTACs |
Proteolysis-targeting chimeras |
SAHA |
Suberoylanilide hydroxamic acid |
CTLs |
Cytotoxic T lymphocytes |
siRNAs |
Small interfering RNAs |
NPs |
Nanoparticles |
CL-siSOX2 |
siSOX2 delivered by cationic lipoplex |
RGDfC-SeNPs |
RGDfC-modified functionalized selenium nanoparticles |
ATFs |
Artificial transcription factors |
ZF |
Zinc-finger |
SRR1 |
SOX2 regulatory region I |
SKD |
Kruppel Associated box |