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Resistance phenotypes obtained with OprD-deficient mutant PASE1 after exposure to carbapenems
| Antibiotic | MICs (μg/ml)
|
||||
|---|---|---|---|---|---|
| PAO1 | PASE1 | PA1433 | PA1434 | PA1436 | |
| Imipenem | 1 | 16 | 16 | 16 | 16 |
| Meropenem | 0.5 | 4 | 8 | 8 | 2 |
| ER-35786 | 0.25 | 1 | 4 | 1 | 8 |
| Carbenicillin | 64 | 64 | 64 | 256 | 32 |
| Cefpirome | 2 | 2 | 2 | 4 | 4 |
| Gentamicin | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 |
| Chloramphenicol | 64 | 64 | 64 | 128 | 32 |
| Sparfloxacin | 0.5 | 0.5 | 1 | 1 | 2 |
