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Effect of ecto-nucleotidases’ activities on acupuncture analgesia of ankle AA rats. ARL (100 μM, 50 μL) was pre-injected in ST36 20 min ahead of needling (n = 4–5). Apyrase (50 units/mL, 50 μL), soluble form of CD 39, was administrated at the same time point, 50 min before the behavioral test. Establishing the inflammation pain and acupuncture intervention was referred to in Figure 5. The data are based on Zuo et al. 2022 [74].
