Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Tumour clonal representation in traditional tissue biopsies and liquid biopsies. Traditional tissue biopsies are rich in tumour DNA but can be naïve to tumour heterogeneity. Liquid biopsies of circulating cell-free DNA (cirDNA) in blood are diluted with DNA from normal tissue. Liquid biopsies of cell-free DNA from non-blood sources can capture disease heterogeneity better than tissue biopsies with far less dilution with healthy DNA than cirDNA.
