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. 2022 Mar 3;14(5):1309. doi: 10.3390/cancers14051309

Table 1.

Concordance in variants detected in tumour tissue and cfDNA from body fluids.

Fluid Concordance between Sources Additional Variants in Tissue Additional Variants in Fluid Source
Ascites 80% (n = 5) 20% (n = 1) 0% (n = 0) Perrone, M.E. et al., 2021 [26]
100% (n = 2) 0% (n = 0) 0% (n = 0) Yang, S.R. et al., 2019 [27]
10% (n = 1) 60% (n = 6) 70% (n = 7) Han, M.R. et al., 2020 [25]
88% (n = 23) 0% (n = 0) 12% (n = 3) Leick, K.M. et al., 2020 [34]
CSF 44% (n = 4) 0% (n = 0) 56% (n = 5) Duan, H. et al., 2020 [28]
Pleural
effusions
75% (n = 12) 19% (n = 3) 6% (n = 1) Perrone, M.E. et al., 2021 [26]
75% (n = 6) 0% (n = 0) 25% (n = 2) Yang, S.R. et al., 2019 [27]
100% (n = 6) 0% (n = 0) 0% (n = 0) Mokanszki, A. et al., 2021 [32]
58% (mutations = 96) 18% (mutations = 29) 24% (mutations = 40) Tong, L. et al., 2019 [33]
50% (n = 7) 36% (n = 5) 21% (n = 3) Guo, Z. et al., 2019 [36]

n—number of people, CSF—cerebrospinal fluid.