Appendix Table 4.
Multi-variables adjusted odds ratio of diabetes incident associated with Se stratums, sub-categorized by triglyceride levels
| TG subgroups | Stratums | Incidence cases, n | Control, n | OR*(95% CI) Crude | OR† (95% CI) Model 1 | OR‡ (95% CI) Model 2 |
|---|---|---|---|---|---|---|
|
| ||||||
| Low (<1.70 mmol/L) | Q1 | 57 (22.71) | 105 (26.79) | 1.00 | 1.00 | 1.00 |
| Q2 | 52 (20.72) | 97 (24.74) | 1.03 (0.53–2.01) | 1.08 (0.66–1.79) | 0.95 (0.53–1.70) | |
| Q3 | 74 (29.48) | 109 (27.81) | 0.87 (0.46–1.62) | 1.37 (0.86–2.19) | 1.20 (0.71–2.05) | |
| Q4 | 68 (27.09) | 81 (20.66) | 1.23 (0.65–2.33) | 1.82 (1.10–3.01) | 1.66 (0.96–2.83) | |
| ρ for trend: 0.61 | ρ for trend: 0.04 | ρ for trend: 0.10 | ||||
|
| ||||||
| Median (1.70~2.25 mmol/L) | Q1 | 22 (16.42) | 21 (19.63) | 1.00 | 1.00 | 1.00 |
| Q2 | 32 (23.88) | 28 (26.17) | 1.09 (0.50–2.39) | 1.23 (0.50–3.07) | 0.84 (0.28–2.57) | |
| Q3 | 34 (25.37) | 24 (22.43) | 1.35 (0.61–2.99) | 1.69 (0.69–4.18) | 2.00 (0.63–6.34) | |
| Q4 | 46 (34.33) | 34 (31.78) | 1.29 (0.61–2.72) | 1.74 (0.74–4.13) | 1.37 (0.44–3.62) | |
| ρ for trend: 0.24 | ρ for trend: 0.39 | ρ for trend: 0.40 | ||||
|
| ||||||
| High (≥2.25 mmol/L) | Q1 | 44 (18.57) | 29 (23.58) | 1.00 | 1.00 | 1.00 |
| Q2 | 42 (17.72) | 31 (25.20) | 0.89 (0.46–1.73) | 0.99 (0.48–2.03) | 1.18 (0.52–2.67) | |
| Q3 | 68 (28.69) | 22 (17.89) | 2.04 (1.04–3.99) | 2.58 (1.26–5.28) | 2.20 (1.04–5.04) | |
| Q4 | 83 (35.02) | 41 (33.33) | 1.33 (0.73–2.43) | 1.46 (0.76–2.79) | 1.14 (0.53–2.49) | |
| ρ for trend: 0.19 | ρ for trend: 0.23 | ρ for trend: 0.94 | ||||
Note: The interaction test between triglyceride categories and serum Se stratums: F=7.09, ρ<0.0001.
: Represent the crude odds ratios
: Odds ratios were adjusted by age at diagnosis (<30, 30–39, 40–49, 50–59, 60–69, ≥70), gender (male/female), BMIs (<18.5, 18.5–23.9, 24.0–27.9, ≥28.0), family history of diabetes (yes or no), physical exercise (no, occasionally, often), smoking index, (no smoking, 0–6.3, 6.4–14.0, 14.1–23.2, ≥23.3), lifetime total alcohol intake, (no drinking, 0–72.2, 72.3–167.5, 167.5–380.1, ≥380.1), high-density lipoprotein (<1.04 mmol/L, 1.04–1.55 mmol/L, >1.55 mmol/L), low-density lipoprotein (<2.60 mmol/L, 2.60–4.11 mmol/L, >4.12 mmol/L), and hypertension status (normal, elevated, stage I, stage II).
: Odds ratios in model 2 were further adjusted by serum level (μg/L) of Nickel, Cobalt, Copper, Zinc, Cadmium, Mercury, Chromium, Arsenic, and Magnesium (continues variables) on the basis of adjusted confounding factors in model 1.