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. 2022 Feb 23;23(5):2446. doi: 10.3390/ijms23052446

Figure 3.

Figure 3

Inflammation and apoptosis-related gene expression in APP/BIN1/COPS5 3xTg-AD mice. TNFα (A), IL-6 (A), NOS3 (B), and COX-2 (B) mRNA levels were analyzed in wild-type (n = 4) and APP/BIN1/COPS5 3xTg-AD (n = 4) mice. Data are expressed as mean ± S.E.M. and as fold-changes compared to mRNA levels in wild-type mice; * p < 0.05.