TNBC |
Triple Negative Breast Cancer |
ER |
Estrogen Receptor |
PR |
Progesterone Receptor |
HER2 |
Human Epidermal Growth Factor Receptor 2 |
IBC |
Inflammatory Breast Cancer |
PI3K |
Phosphoinositide-3-Kinase |
BMI |
Body Mass Index |
TME |
Tumor Microenvironment |
WAT |
White Adipose Tissue |
ECM |
Extracellular Matrix |
ROS |
Reactive Oxygen Species |
RNS |
Reactive Nitrogen Species |
NF-kB |
Factor Kappa-Light-Chain-Enhancer |
STAT-3 |
Signal Transducer and Activator of Transcription Factor 3 |
STAT-5 |
Signal Transducer and Activator of Transcription Factor 5 |
HIF-1a |
Hypoxia-Inducible Factor 1-alpha |
TLR4 |
Toll-like Receptor 4 |
CCL2 |
Monocyte Chemoattractant Protein |
CSF-1 |
Colony-Stimulating Factor-1 |
JNK |
c-jun-NH2 Terminal Protein Kinase |
GM-CSF |
Granulocyte-Macrophage Colony-Stimulating Factor |
SHBG |
Steroid Sex Hormone-Binding Globulin |
TNF-α |
Tumor Necrosis Factor α |
IL |
Interleukin |
IGF-1 |
Insulin-like Growth Factor-1 |
FA |
Fatty Acid |
TCA |
Tricarboxylic Acid |
FASN |
Fatty Acid Synthase |
TAG |
Triglycerides or Triacylglycerol |
SREBPs |
Sterol Element-Binding Proteins |
UPR |
Uncoupled Protein Response |
ATGL |
Adipocyte Triglyceride Lipase |
HSL |
Hormone-Sensitive Lipase |
MAGL |
Monoacylglycerol Lipase |
FAT |
Fatty Acid Translocase |
FABP-4 |
Fatty Acid-Binding Protein 4 |
PUFAs |
Polyunsaturated Fatty Acids |
EMT |
Epithelial-to-Mesenchymal Transition |
ZEB-1 |
Zinc Finger E-box-binding Homobox-1 Protein |
ECM |
Extra Cellular Matrix |
MT-MMP |
Membrane-Tethered Matrix Metalloproteases |
MMP |
Matrix Metalloproteases |
RTK |
Receptor Tyrosine Kinase |
EGFR |
Epidermal Growth Factor Receptor |
GEF |
Guanine Nucleotide Exchange Factor |
Ig |
Immunoglobulin |
FAK |
Focal Adhesion Kinase |
GDIs |
Guanine Nucleotide Dissociation Inhibitors |
AMPK |
AMP-Activated Protein Kinase |