Table 4.
Up- and downregulated genes contributing to KEGG pathway and enriched gene sets.
| Upregulated Genes | ||
| Ensemble ID | Gene Names | Protein Names |
| ENSTGUG00000007300 | TPH2 | Tryptophan hydroxylase 2 |
| ENSTGUG00000009295 | TH | Tyrosine hydroxylase |
| ENSTGUG00000005959 | CHAT | Choline-O-acetyl transferase |
| ENSTGUG00000011058 | SLC18A2 | Solute carrier family 18 member A2 (synaptic vesicular monamine transporter) |
| ENSTGUG00000009694 | SLC5A7 | Choline:sodium symporter (presynaptic sodium-dependent high-affinity choline transporter 1) |
| ENSTGUG00000005989 | SLC18A3 | Solute carrier family 18 member A3 (synaptic vesicular acetylcholine transporter) |
| ENSTGUG00000007218 | SLC6A2 | Monoamine transmembrane transporter |
| ENSTGUG00000008069 | SLC10A4 | Solute carrier family 10 member A4 (acidification of synaptic vesicles containing monoamines) |
| Downregulated Genes | ||
| Ensemble ID | Gene Names | Protein Names |
| ENSTGUG00000017017 | POMC | Pro-opiomelanocortin |
| ENSTGUG00000002625 | EDNRA | Endothelin receptor |
| ENSTGUG00000013478 | P2RY2 | Purinergic receptor P2Y2 |
| ENSTGUG00000010805 | TCF7L2 | RNA polymerase II proximal promoter sequence-specific DNA binding protein (Transcription factor 7 like 2) |
| ENSTGUG00000009947 | MSX1 | RNA polymerase II-specific DNA-binding transcription activator |
| ENSTGUG00000009095 | CRYM | Crystallin mu |
| ENSTGUG00000012325 | SLCO1C1 | Thyroid hormone transporter |
Table 4 lists the genes, which changed significantly based on p-value and also contributed to the significantly altered pathways. Some of them are DEGs because their fold change reached the limit (log2FC value was ±1.5); others are not DEGs because of their smaller fold change.