Table 2.

Molecules produced and secreted by endothelial cells.

Regulation of Vascular Tone	(a)Vasodilation: nitric oxide, prostacyclin, endothelium-derived hyperpolarizing factors, adenosine
	(b)Vasoconstriction: endothelin-1, angiotensin II, thromboxane A2, reactive oxygen species
Balanced Blood Fluidity/Thrombosis	(a)Coagulation: heparin cofactor 2, factor V, protein S, protein C, thrombomodulin, tissue factor, von Willebrand factor
	(b)Fibrinolysis: tissue plasminogen activator, prostaglandins, plasminogen activator inhibitor type 1, urokinase
Vascular Inflammation and Immunological Process Control	(a)Cytokines: interleukins 1,6,8, monocyte chemoattractant protein-1
	(b)Adhesion Molecules: vascular adhesion protein 1, intercellular adhesion molecule 1, selectins
	(c)Growth Factors: Basic fibroblast growth factor, insulin-like growth factor, platelet-derived growth factor, transforming growth factor, tumour necrosis factor