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. 2022 Feb 27;23(5):2615. doi: 10.3390/ijms23052615

Figure 2.

Figure 2

Comparison of (a) viability, (b) proliferation, and (c,d) migration of dental pulp stem cells (DPSC) and stem cells from the apical papilla (SCAP). (a,b) Viability and proliferation of DPSC and SCAP at different serum concentrations. Median values and 25–75% percentiles are based on three independent experiments performed in triplicates (n = 9). For each time point, the same lower-case letters indicate bars with statistically significant difference (p ≤ 0.05). (c) Cell migration of both cell types was determined over 72 h in triplicates and repeated two times (n = 12). Medians and 25–75% percentiles were normalized to the initial wound area, which was set to 100%. (d) Microscopic images of gap closure (gap area highlighted in yellow) by DPSC and SCAP cultured in alpha minimum essential medium (αMEM) with 10% fetal bovine serum (FBS) with and without Locostatin over 72 h. Scale bars: 400 µm.