Table 1.
Sperm Quality | Molecular Mechanism | References | |
---|---|---|---|
Cholesterol | ↓ | ↓ membrane fluidity ↓ testosterone synthesis ↑ oxidative stress |
[55,71] |
SFA | ↓ | ↑ insulin resistance ↓ sperm mitochondrial function ↑ oxidative stress |
[4] |
MUFA | ↑ | ↑ membrane fluidity ↑ sperm mitochondrial function ↓ oxidative stress |
[5,7,61] |
PUFA | ↑ | ↓ insulin resistance ↓ lipogenesis ↑ membrane fluidity ↑ sperm mitochondrial function ↓ oxidative stress |
[5,57] |
Carbohydrates | ↓ (high sugar intake) |
↑ insulin resistance ↓ testosterone synthesis ↑ oxidative stress small RNA profiles |
[74,75,79] |
Proteins | ↓ (low protein intake) |
↓ testosterone synthesis | [84] |