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. 2022 Feb 25;23(5):2542. doi: 10.3390/ijms23052542

Table 1.

Effects of nutrients on sperm quality.

Sperm Quality Molecular Mechanism References
Cholesterol ↓ membrane fluidity
↓ testosterone synthesis
↑ oxidative stress
[55,71]
SFA ↑ insulin resistance
↓ sperm mitochondrial function
↑ oxidative stress
[4]
MUFA ↑ membrane fluidity
↑ sperm mitochondrial function
↓ oxidative stress
[5,7,61]
PUFA ↓ insulin resistance
↓ lipogenesis
↑ membrane fluidity
↑ sperm mitochondrial function
↓ oxidative stress
[5,57]
Carbohydrates
(high sugar intake)
↑ insulin resistance
↓ testosterone synthesis
↑ oxidative stress
small RNA profiles
[74,75,79]
Proteins
(low protein intake)
↓ testosterone synthesis [84]