Table 1.

Clinical trials of neoantigens vaccines.

Clinical Trials	Tumor	Vaccines	Reference
NCT00683670	Melanoma	Dendritic Cell	Carreno et al., 2015 [60]
NCT01970358	Melanoma	Peptide	Ott et al., 2017 [61]
NCT02035956	Melanoma	mRNA	Sahin et al., 2017 [62]
NCT02149225	Glioblastoma	Peptide	Hilf et al., 2019 [63]
NCT02287428	Glioblastoma	Peptide	Keskin et al., 2019 [64]
NCT02510950	Glioblastoma	Peptide	Johanns et al., 2019 [65]
NCT02897765	Advanced melanoma/Non-small cell lung cancer/Bladder cancer	Peptide + aPD-1	Ott et al., 2020 [66]
NCT03171220	Thymoma/Pancreatic cancer	Dendritic Cell	Chen et al., 2019 [67]
NCT01461148	Colorectal cancer	Peptide	Kloor et al., 2020 [68]
NCT03480152	Gastrointestinal cancer	mRNA	Cafri et al., 2020 [69]
NCT03662815	Melanoma/Colon Cancer/Non-small cell lung cancer/Pancreatic Cancer/Biliary Tract Cancer/Ovarian Cancer	Peptide	Fang et al., 2020 [70]
NCT01970358	Melanoma	Peptide	Hu et al., 2021 [71]
NCT03645148	Advanced pancreatic cancer	Peptide	Chen et al., 2021 [72]
NCT02454634	Gliomas	Peptide	Platten et al., 2021 [73]