Table 1.
Clinical Characteristics and Laboratory Data of the Four Patients
| Items | Case 1 | Case 2 | Case 3 | Case 4 |
|---|---|---|---|---|
| Sex, age (years) | Male, 64 | Male, 54 | Male, 46 | Male, 56 |
| History of bird contact | Parrots | Dead birds | Geese | Chickens |
| Underlying diseases | Diabetes | Coronary heart disease, hypertension | Hypertension | None |
| Symptoms | Fever, fatigue, muscle soreness, cough, expectoration, nausea, and vomiting | Fever, fatigue, muscle soreness, cough, poor consciousness | Fever, fatigue, muscle soreness, cough, expectoration, shortness of breath, diarrhea | Fever, fatigue, cough, expectoration |
| HCO3 (normal: 22–28 mmol/L) | 19.54 | 29.6 | 24.4 | 22.3 |
| WBC (normal: 4–10×109/L) | 13.31 | 3.2 | 6.17 | 5.88 |
| Absolute neutrophil count(normal:2–7×109/L) | 12.05 | 2.28 | 5.45 | 4.76 |
| Neutrophil percentage (normal: 50–70%) | 90.5 | 88.2 | 88.3 | 80.6 |
| CRP (normal: 0–8 mg/L) | 89 | 229.5 | 179.96 | 147.79 |
| PCT (normal: 0–5 ng/mL) | 4.75 | 4.26 | 1.16 | 1.15 |
| CK (normal: 26–174 U/L) | 20,252 | 7659 | 2363 | 5066 |
| CK-MB (normal:0–24U/L) | 23 | 19 | 20 | 17 |
| High-sensitivity troponin T(normal:0–14ng/L) | 13 | 11 | 12 | 11.53 |
| Myoglobin (normal: 0–110 ng/mL) | 823.13 | 613.5 | 867.5 | 534.21 |
| BNP (normal: 0–100 pg/mL) | 4246 | 1669 | 1461 | 1388 |
| AST (normal: 13–40 U/L) | 348 | 258 | 81.7 | 141 |
| ALT (normal: 5–40 U/L) | 70 | 72 | 48.4 | 141 |
| LDH (normal: 0–247 U/L) | 576 | 669 | 461 | 388 |
| Cr (normal: 59–104 µmol/L) | 178 | 257 | 111 | 137 |
| Urea (normal: 3.2–7.1 µmol/L) | 11.34 | 12.02 | 8.21 | 10.3 |
| eGFR(normal:80–120 mL/min) | 34.69 | 23.87 | 69.69 | 50.36 |
| Ca (normal: 2.25–2.75 mmol/L) | 1.87 | 1.74 | 1.68 | 1.85 |
| P (normal: 0.96–1.62 mmol/L) | 1.42 | 0.51 | 0.55 | 0.76 |
| Fibroblasts (normal: 2–4 g/L) | 12.54 | 6.65 | 4.71 | 6.58 |
| D-dimer (normal: 0–0.5 mg/L) | 2.26 | 2.13 | 3.44 | 1.3 |
| mNGS C. psittaci reads (n) | 1255 | 1178 | 1563 | 3102 |
| McMahon score | 9 | 9.5 | 5 | 8 |
Abbreviations: AST, aspartate aminotransferase; BNP, brain natriuretic peptide; CK, creatine kinase; Cr, creatinine; CRP, C-reactive protein; LDH, lactate dehydrogenase; PCT, procalcitonin; WBC, white blood cell.