Table 5.

Effects of dietary agents on tumor spheroid formation in 850 ^MIN COL model.

Dietary Agent	Tumor Spheroid Number a	p Value	Relative to Solvent Control
EtOH	24.8 ± 2.2
CUR	4.0 ± 0.4	0.010	−83.9%
EGCG	6.0 ± 1.3	0.030	−68.8%
EPA	6.4 ± 1.4	0.030	−66.7%
DHA	6.8 ± 1.4	0.030	−64.5%
CA	8.6 ± 1.9	0.042	−55.5%

^a determined at day 14 after seeding 100 cells. Data expressed as mean ± SD, n = 3 per treatment group and analyzed by one-way ANOVA with Dunnett’s multiple comparison test (α = 0.05). SD, standard deviation; ANOVA, analysis of variance. EtOH, ethanol; CUR, curcumin; EGCG, epigallocatechin gallate; EPA, eicosa pentaenoic acid; DHA, docosa hexaenoic acid; CA, carnosic acid.