| Abcc6 | ATP binding cassette subtype C number 6 |
| ABE | Adenine base editor |
| Abhd6 | Alpha/beta-hydrolase domain 6 |
| Adora2a | Adenosine 2a receptor |
| α-Gal A | α-galactosidase A |
| Agxt | Alanine-glyoxylate aminotransferase |
| Ahr | Aryl hydrocarbon receptor |
| Aire | Autoimmune regulator |
| ALS | Amyotrophic lateral sclerosis |
| Angptl8 | Angiopoietin-like protein 8 |
| Anks3 | Ankyrin repeat and sterile alpha motif domain containing 3 |
| APECED | Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy |
| ApoE | Apolipoprotein E |
| AS | Angelman syndrome |
| AsCpf1 | Acidaminococcus sp. Cpf1 |
| ASD | Autism spectrum disorder |
| Asip | Agouti signaling protein |
| Atg16l1 | Autophagy-related 16-like 1 |
| B2m | Beta-2-microglobulin |
| BE | Base-editing |
| BlatCas9 | Brevibacillus laterosporus Cas9 |
| Bmpr2 | Bone morphogenetic protein receptor 2 |
| BN | Brown Norway |
| C3 | Complement C3 |
| C9orf72 | Chromosome 9 open reading frame 72 |
| Cas12a | CRISPR-associated protein 12a |
| Calb2 | Calbindin 2 |
| Carns1 | Carnosine synthase 1 |
| Cas9n | Cas9 nickase |
| CBE | Cytosine base editor |
| Ccdc85c | Coiled-coil domain containing 85C |
| Cck | Cholecystokinin |
| CD | Crohn’s disease |
| CES2 | Carboxylesterase 2 |
| Ces2a | Carboxylesterase 2A |
| CF | Cystic fibrosis |
| Cftr | Cystic fibrosis transmembrane conductance regulator |
| CIPN | Chemotherapy-induced peripheral neuropathy |
| Cirp | Cold-inducible RNA-binding protein |
| CLICK | CRISPR with lssDNA inducing conditional knockout alleles |
| Cp | Ceruloplasmin |
| Cpf1 | CRISPR from Prevotella and Francisella1 |
| Cplx1 | Complexin I |
| Cre-ERT2 | Cre recombinase-estrogen receptor T2 |
| Crhr1 | Corticotropin releasing hormone receptor 1 |
| CRISPR/Cas9 | Clustered regularly interspaced palindrome repeats (CRISPR)/Caspase 9 (Cas9) |
| Cas12a | Type V CRISPR-effector protein (formerly Cpf1) |
| crRNA | CRISPR RNA |
| CS | Cockayne syndrome |
| Csb | Cockayne syndrome B |
| Cyp2c11 | Cytochrome P450, subfamily 2, polypeptide 11 |
| Cyp2d | Cytochrome P450 family 2 subfamily D member 6 |
| Cyp2e1 | Cytochrome P450 2E1 |
| Cyp2J2 | Cytochrome P450 family 2 subfamily J member 2 |
| Cyp2J3 | Cytochrome P450, family 2, subfamily j, polypeptide 3 |
| Cyp2J10 | Cytochrome P450, family 2, subfamily j, polypeptide 10 |
| Cyp3a1 | Cytochrome P450 3A1 |
| Cyp3a2 | Cytochrome P450 3A2 |
| Cyp24a1 | Cytochrome P450 family 24 subfamily A member 1 |
| Cyp27b1 | Cytochrome P450 family 27 subfamily B member 1 |
| DA | Dark agouti |
| Dat | Dopamine transporter |
| db | Diabetes |
| Dbndd1 | Dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| Defb23 | Defensin beta 23 |
| Defb26 | Defensin beta 26 |
| Defb42 | Defensin beta 42 |
| dCas9 | Dead Cas9 |
| DdCBE | DddA-derived cytosine base editor |
| DddA | Bacterial toxin deaminase |
| Depdc5 | DEP domain-containing 5 |
| Des | Desmin |
| DdCBE | DddA-derived cytosine base editor |
| DMD | Duchenne muscular dystrophy |
| Dmd | Dystrophin-coding gene (dystrophin) |
| DKO | Double KO |
| DNA-PKcs | DNA-dependent protein kinase catalytic subunits |
| Dnah17 | Dynein axonemal heavy chain 17 |
| Drd1a | Dopamine receptor D1A |
| DSB | Double-stranded break |
| dsDNA | Double-stranded DNA |
| dsRed | Discosoma coral red fluorescent protein |
| EGFP | Enhanced green fluorescent protein |
| EndoMT | Endothelial-to-mesenchymal transition |
| EP | Electroporation |
| Epsti1 | Epithelial stromal interaction 1 |
| Erbb3 | Erb-B2 receptor tyrosine kinase 3 |
| ERV | Endogenous retroviral element |
| ES | Embryonic stem |
| Esr1 | Estrogen receptor 1 |
| ET | Egg transfer |
| F344 | Fisher 344 |
| F8 | Factor 8 |
| Fabp2 | Fatty acid binding protein 2 |
| Fah | Fumarylacetoacetate hydrolase |
| FD | Fabry disease |
| Fh | Fumarate hydratase |
| FH | Familial hypercholesterolemia |
| FHH | Fawn-hooded hypertensive |
| Fmr1 | Fragile X mental retardation 1 |
| FMRP | Fragile X mental retardation protein |
| FnCas9 | Francisella novicida Cas9 |
| Foxp3 | Forkhead box P3 |
| Foxn1 | Forkhead box N1 |
| FSG | F344-scid gamma |
| Fus | Fused in sarcoma |
| FXS | Fragile X syndrome |
| Gaa | Acid alpha-glucosidase |
| Gad1 | Glutamate decarboxylase 1 |
| GAD67 | Glutamate decarboxylase 67-kDa isoform |
| GE | Genome editing or genome-edited |
| GFP | Green fluorescent protein |
| G6pd | Glucose-6-phosphate dehydrogenase |
| GM | Genetically modified |
| GOI | Gene of interest |
| GONAD | Genome-editing via oviductal nucleic acids delivery |
| GR | Glucocorticoid receptors |
| GRdim | Glucocorticoid receptor mutant |
| Grin1 | Glutamate ionotropic receptor N-methyl-D-aspartate (NMDA) type subunit 1 |
| gRNA | Guide RNA |
| Gsd2 | Glycogen storage disease type 2 |
| GSDII | Glycogen storage disease type II (GSDII) |
| 2H2OP | Two-hit by gRNA and two-oligo with plasmid |
| HA | Hereditary aceruloplasminemia |
| HCD | High-cholesterol diet |
| HDR | Homology directed repair |
| Hemgn | Hemogen |
| hhy | Hemorrhagic hydrocephalus |
| Hprt1 | Hypoxanthine phosphoribosyltransferase 1 |
| HR | Homologous recombination |
| HT1 | Hereditary tyrosinemia type I |
| Htr7 | 5-hydroxytryptamine receptor 7 |
| IC | Intracytoplasmic injection |
| Ighm | Immunoglobulin heavy constant mu |
| IgM | Immunoglobulin M |
| i-GONAD | Improved GONAD |
| Il2rg | Interleukin 2 receptor gamma |
| indels | Insertion or deletion of nucleotides |
| iNOS | Inducible nitric oxide synthase |
| IRES | Internal ribosomal entry site |
| IVF | In vitro fertilized |
| Kat II | Kynurenine aminotransferase II |
| Kcnj16 | Potassium inwardly-rectifying channel, subfamily J, member 16 |
| Kcnk3 | Potassium channel subfamily K member 3 |
| KI | Knock-in |
| Kit | Kit proto-oncogene |
| KO | Knockout |
| L1cam | L1 cell adhesion molecule |
| LbCpf1 | Lachnospiraceae bacterium Cpf1 |
| L dlr | Low-density lipoprotein receptor |
| Lrat | Lecithin retinol acyltransferase |
| Lepr | Leptin receptor |
| LE | Long–Evans |
| LEH | Long–Evans hooded |
| Lepr | Leptin receptor |
| LEW | Lewis |
| Lgr5 | Leucine-rich repeat-containing G-protein coupled receptor 5 |
| lncRNA | Long non-coding RNA |
| Lrat | Lecithin retinol acyltransferase |
| lssDNA | Long single-stranded DNA |
| Mc3r | Melanocortin 3 receptor |
| Mc4r | Melanocortin 4 receptor |
| Mdr1a | Multidrug resistance protein 1a |
| Mdr1b | Multidrug resistance protein 1b |
| Mdx | X-linked muscular dystrophy |
| Mecp2 | Methyl-CpG-binding protein 2 |
| MI | Microinjection |
| mitoTALE | TALE nickase enabling mitochondrial gene editing |
| Mkx | Mohawk homeobox |
| Mnx1 | Gene encoding homeobox protein HB9 |
| mtDNA | Mitochondrial DNA |
| mTORC1 | Rapamycin complex 1 signaling pathway |
| Myl4 | Myosin light-chain 4 |
| NAFLD | Nonalcoholic fatty liver disease |
| nCas9 | Cas9 nickase |
| Ndst1 | N-deacetylase |
| Ndst4 | N-sulfotransferase 4 |
| Nes | Nestin |
| Nfatc1 | Nuclear factor of activated T-cells |
| Ngln3 | Neuroligin 3 |
| NHEJ | Non-homologous end joining |
| Nkx3.1 | NK3 homeobox 1 |
| NmCas9 | Neisseria meningitidis Cas9 |
| Nr3c1 | Nuclear receptor subfamily 3, group C, member 1 |
| Nrf2 | Nuclear factor (erythroid-derived 2)-like-2 |
| Oatp1b2 | Organic anion transport polypeptide 1b2 |
| Ogdh | Oxoglutarate dehydrogenase |
| PAH | Pulmonary arterial hypertension |
| PAM | Protospacer adjacent motif |
| PB | PiggyBack transposon |
| PBS | Phosphate-buffered saline |
| PE | Prime editing |
| PGK | Phosphoglycerate kinase |
| PH | Pulmonary hypertension |
| PH1 | Primary hyperoxaluria type 1 |
| PI | Pronuclear injection |
| PMCA4 | Plasma membrane calmodulin–dependent calcium ATPase isoform 4 |
| PMS | Phelan–McDermid syndrome |
| Pnpla5 | Patatin-like phospholipase domain containing 5 |
| poly(A) | Polyadenine tails |
| Pomc | Proopiomelanocortin |
| Pp | Poring pulse |
| PPi | Pyrophosphate |
| Prf1 | Perforin 1 |
| Prkdc | DNA-dependent protein kinase catalytic subunit |
| Psen1 | Presenilin 1 |
| p52SHC/p46SHC | Adaptor protein 1 (shc1), encodes 3 main protein isoforms |
| Pvalb | Parvalbumin |
| PVG | Piebald Virol Glaxo |
| PXE | Pseudoxanthoma elasticum |
| Pxr | Pregnane X receptor |
| rAAV | Recombinant adeno-associated virus |
| Rab38 | Ras-related protein Rab-38 |
| Rag1 | Recombination activating gene 1 |
| Rag2 | Recombination activating gene 2 |
| RD | Retinal dystrophy |
| R en | Renin |
| Rffl-lnc1 | A gene located within the 5′UTR intronic region of the rififylin (Rffl) gene |
| rGONAD | Rat-based i-GONAD |
| RNaseT2 | Ribonuclease T2 |
| RNP | Ribonucleoprotein |
| Rosa26 | Gt(ROSA)26Sor |
| RP | Retinitis pigmentosa |
| RS | Rett syndrome |
| SaCas9 | Staphylococcus aureus Cas9 |
| SCID | Severe combined immunodeficiency |
| SD | Sprague–Dawley |
| SERCA2a | Sarcoplasmic reticulum Ca2+-ATPase |
| sgRNA | Single-guide RNA |
| Shank3 | SH3 and multiple ankyrin repeat domains 3 |
| Sirpa | Signal regulatory protein alpha |
| Slc6 | Sodium- and chloride-dependent members of the solute carrier family 6 |
| Slc16a2 | Solute carrier family 16 member 2 coding for monocarboxylate transporter 8 (MCT8) |
| Slco1b2 | Solute carrier organic anion transporter family member 1B2 |
| SNP | Single-nucleotide polymorphism |
| Sox10 | Sry-box transcription factor 10 |
| Sox16 | SRY (sex determining region Y)-box 16 |
| SS | Dahl salt-sensitive |
| SSCs | Spermatogonial stem cells |
| ssDNA | Single-stranded DNA |
| ssODN | Single-stranded oligodeoxynucleotide |
| St1Cas9 | Streptococcus thermophilus Cas9 |
| STs | Seminiferous tubules |
| TAKE | Technique for Animal Knockout system by Electroporation |
| TALE | Transcriptional activator-like effector |
| TALENs | Transcription activator-like effector nucleases |
| Tet1 | Tet methylcytosine dioxygenase 1 |
| Tet2 | Tet methylcytosine dioxygenase 2 |
| Tet3 | Tet methylcytosine dioxygenase 3 |
| Tg | Transgenic |
| Th | Tyrosine hydroxylase |
| Thy1 | Thy-1 cell surface antigen |
| Tie2 | Tunica interna endothelial cell kinase 2 |
| Tlr4 | Toll-like receptor 4 |
| TM/Kyo | TRM or tremor rat |
| Tp | Transfer pulse |
| Tp53 | Tumor protein p53 |
| tracrRNA | Trans-activating CRISPR RNA |
| Trdmt1 | TRNA aspartic acid methyltransferase 1 |
| Trpa1 | Transient receptor potential family member ankyrin 1 |
| Trpv4 | Transient receptor potential cation channel subfamily V member 4 |
| Tyr | Tyrosinase |
| Ube3a | Ubiquitin protein ligase E3A |
| Uox | Urate oxidase (uricase) |
| Vapb | Vesicle-associated membrane protein-associated protein B/C |
| Vdr | Vitamin D receptor |
| Wfs1 | Wolfram syndrome 1 |
| WI | Wistar |
| WI-IM | Wistar–Imamichi |
| WKY | Wistar–Kyoto |
| Wnt1 | Wnt family member 1 |
| WS | Wolfram syndrome |
| WT | Wild-type |
| XLH | X-linked hydrocephalus |
| X-SCID | X-linked severe combined immunodeficiency |
| ZF | Zinc-finger |
| ZFNs | Zinc-finger nucleases |
| ZP | Zona pellucida |