Figure 2.

Detection of domain sequences of select NP classes in Lake Huron sediment. Figures 2A–D show the detection and relative read abundance of cyclomarin, surugamide, pyoverdin, and coelichelin classes, respectively. Figures S3–5 depict the distribution of additional NP classes. Different sized circles represent sequence read abundance at a rarefaction depth of 13 sequences per sample for KSα domain sequences and of 3,487 sequences per sample for A domain sequences at each collection site in Lake Huron. Representative structures from each of the four compound classes are shown in Figures 1E–H.