Table 4.
DAMPs in ocular cancer.
| Disease | DAMPs | Type | Origin | Localization |
|---|---|---|---|---|
Ocular cancer
|
S100 [83] | Ca2+ binding protein | Cytoplasmic | Astrocytes/ganglion cell/Müller glia |
| S100A1 [86] | Ca2+ binding protein | Cytoplasmic | Uveal melanoma | |
| S100B [87] | Ca2+ binding protein | Cytoplasmic | Serum | |
| Uric acid [88] | Metabolic product | Cytoplasmic | Aqueous | |
| HSP70, HSP90 [89,90] | Molecular chaperones | Cytoplasmic | Retina/extracellular vesicles | |
| HMGB1 [91] | Nuclear binding protein | Nuclear | Retinoblastoma | |
| cfcDNA [92] | Nucleic acid | Nuclear | Plasma | |
| Versican [93] | Proteoglycan | ECM | Uveal melanoma |