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. 2022 Mar 2;23(5):2753. doi: 10.3390/ijms23052753

Table 2.

Multivariable Cox hazards analysis of colorectal cancer patients.

Hazard 95% CI
Ratio Min Max p-Value
Well to moderately differentiated histology 0.25 0.13 0.47 <0.0001
Age (<70) 0.50 0.29 0.86 0.012
SPATA18 high 0.55 0.32 0.94 0.029
Lymph node metastasis 1.98 1.14 3.45 0.015
Peritoneal metastasis 5.45 3.05 9.73 <0.0001

The multivariable Cox hazards analysis model initially included sex, age, primary tumor location, tumor size, pT stage, operation status, tumor histology, mucus production, lymph node metastasis, distant organ metastasis, peritoneal metastasis, mismatch repair system status, and immunohistochemistry for SPATA18. A backward elimination with a threshold of p = 0.05 was used to select variables in the final model.