Table 5.
Unadjusted hazard ratio with Cox proportional hazard method for death in lipid HCC metabolism and multivariate analysis of lipid components when adjusted to MELD and HVPG.
| Univariate Analysis | Multivariate Analysis | |||||
|---|---|---|---|---|---|---|
| Parameter | HR | 95% CI | p | HR | 95%CI | p |
| Arachidonic acid | 1.56 | (0.52–4.69) | 0.429 | 12.08 | (2.95–49.93) | 0.027 |
| 1,25 dihydroxy Cholesterol | 5.29 | (1.86–15.08) | 0.002 | 10.61 | (1.37–82.3) | 0.024 |
| Myristyl palmitate | 16.67 | (2.3–120.69) | 0.005 | 31.63 | (1.51–661.66) | 0.026 |
| 12-keto deoxycholic acid | 4.96 | (1.45–17) | 0.011 | 12.98 | (1.39–121.39) | 0.025 |
| LysoPC (21:4) | 4.86 | (1.81–13.01) | 0.002 | 10.46 | (1.41–77.54) | 0.022 |
| LysoPE (22:2) | 1.54 | (1.16–2.03) | 0.002 | 2.37 | (1.07–5.24) | 0.032 |
MELD = model for end-stage liver disease; HVPG = hepatic venous pressure gradient; lysoPC = lysophosphatidylcholine; lysoPE = lysophosphatidylethanolamine.