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. 2022 Mar 2;11(5):1369. doi: 10.3390/jcm11051369

Table 1.

Demographics and clinical characteristics of patients.

NAR
(n = 174)
AR
(n = 812)
p-Value
Age (years) 54 (49–61) 54 (47–61) 0.296
Sex 0.081
Male 145 (83.3) 628 (77.3)
Female 29 (16.7) 184 (22.7)
Child–Turcotte–Pugh class 0.145
A 172 (98.9) 810 (99.8)
B 2 (1.1) 2 (0.2)
Primary liver disease 0.016
HBV 136 (78.2) 642 (79.1)
HCV 17 (9.8) 38 (4.7)
NBNC 21 (12.1) 132 (16.3)
ASA PS classification 0.100
21 (12.1) 114 (14.0)
127 (73.0) 616 (75.9)
26 (14.9) 82 (10.1)
Preoperative TACE 44 (25.3) 169 (20.8) 0.193
Preoperative laboratory result
AFP (ng/mL) 30.0 (8.0–484.0) 50.0 (6.0–657.0) 0.591
Platelet (×103/uL) 135.50 (100.0–177.8) 152.00 (119.0–195.3) <0.001
AST (IU/L) 36.00 (29.0–50.8) 36.00 (27.0–52.0) 0.897
ALT (IU/L) 32.00 (22.0–43.0) 33.00 (22.0–51.0) 0.229
Total bilirubin (mg/dL) 0.90 (0.80–1.20) 0.90 (0.70–1.10) 0.008
Albumin (g/dL) 3.70 (3.5–4.0) 3.80 (3.5–4.1) 0.019
PT (%) 87.45 (78.2–95.9) 90.40 (83.0–98.9) <0.001
PT (INR) 1.08 (1.03–1.16) 1.06 (1.01–1.11) <0.001
ICG R15 13.12 (8.5–19.1) 11.38 (7.8–15.9) 0.004
Operation time (min) 171.00 (135.0–215.0) 180.00 (150.0–225.3) 0.003
Postoperative hospital stay (days) 13.00 (12.0–16.0) 14.00 (12.0–17.0) 0.306
Postoperative complication 21 (12.1) 99 (12.2) 0.964
Pathology
Maximum tumour size (cm) 3.5 (2.4–5.0) 4.2 (2.8–7.0) <0.001
Number of tumours 0.215
Solitary 147 (84.5) 714 (87.9)
Multiple 27 (15.5) 98 (12.1)
Edmondson–Steiner grade 0.093
I–II 78 (44.8) 421 (51.8)
III–IV 96 (55.2) 391 (48.2)
Macrovascular invasion 19 (10.9) 114 (14.0) 0.274
Microvascular invasion 25 (14.4) 150 (18.5) 0.198

AFP, alpha-fetoprotein; ALT, alanine aminotransferase; ASA PS, American Society of Anesthesiologists physical status; AST, aspartate aminotransferase; AR, anatomic resection; HBV, hepatitis B virus; HCV, hepatitis C virus; ICG R15, indocyanine green retention rate at 15 min; INR, international normalised ratio; NAR, non-anatomic resection; NBNC, non-HBV non-hepatitis C virus; PT, prothrombin time; TACE, transcatheter arterial chemoembolisation.