Table 1.
NAR (n = 174) |
AR (n = 812) |
p-Value | |
---|---|---|---|
Age (years) | 54 (49–61) | 54 (47–61) | 0.296 |
Sex | 0.081 | ||
Male | 145 (83.3) | 628 (77.3) | |
Female | 29 (16.7) | 184 (22.7) | |
Child–Turcotte–Pugh class | 0.145 | ||
A | 172 (98.9) | 810 (99.8) | |
B | 2 (1.1) | 2 (0.2) | |
Primary liver disease | 0.016 | ||
HBV | 136 (78.2) | 642 (79.1) | |
HCV | 17 (9.8) | 38 (4.7) | |
NBNC | 21 (12.1) | 132 (16.3) | |
ASA PS classification | 0.100 | ||
Ⅰ | 21 (12.1) | 114 (14.0) | |
Ⅱ | 127 (73.0) | 616 (75.9) | |
Ⅲ | 26 (14.9) | 82 (10.1) | |
Preoperative TACE | 44 (25.3) | 169 (20.8) | 0.193 |
Preoperative laboratory result | |||
AFP (ng/mL) | 30.0 (8.0–484.0) | 50.0 (6.0–657.0) | 0.591 |
Platelet (×103/uL) | 135.50 (100.0–177.8) | 152.00 (119.0–195.3) | <0.001 |
AST (IU/L) | 36.00 (29.0–50.8) | 36.00 (27.0–52.0) | 0.897 |
ALT (IU/L) | 32.00 (22.0–43.0) | 33.00 (22.0–51.0) | 0.229 |
Total bilirubin (mg/dL) | 0.90 (0.80–1.20) | 0.90 (0.70–1.10) | 0.008 |
Albumin (g/dL) | 3.70 (3.5–4.0) | 3.80 (3.5–4.1) | 0.019 |
PT (%) | 87.45 (78.2–95.9) | 90.40 (83.0–98.9) | <0.001 |
PT (INR) | 1.08 (1.03–1.16) | 1.06 (1.01–1.11) | <0.001 |
ICG R15 | 13.12 (8.5–19.1) | 11.38 (7.8–15.9) | 0.004 |
Operation time (min) | 171.00 (135.0–215.0) | 180.00 (150.0–225.3) | 0.003 |
Postoperative hospital stay (days) | 13.00 (12.0–16.0) | 14.00 (12.0–17.0) | 0.306 |
Postoperative complication | 21 (12.1) | 99 (12.2) | 0.964 |
Pathology | |||
Maximum tumour size (cm) | 3.5 (2.4–5.0) | 4.2 (2.8–7.0) | <0.001 |
Number of tumours | 0.215 | ||
Solitary | 147 (84.5) | 714 (87.9) | |
Multiple | 27 (15.5) | 98 (12.1) | |
Edmondson–Steiner grade | 0.093 | ||
I–II | 78 (44.8) | 421 (51.8) | |
III–IV | 96 (55.2) | 391 (48.2) | |
Macrovascular invasion | 19 (10.9) | 114 (14.0) | 0.274 |
Microvascular invasion | 25 (14.4) | 150 (18.5) | 0.198 |
AFP, alpha-fetoprotein; ALT, alanine aminotransferase; ASA PS, American Society of Anesthesiologists physical status; AST, aspartate aminotransferase; AR, anatomic resection; HBV, hepatitis B virus; HCV, hepatitis C virus; ICG R15, indocyanine green retention rate at 15 min; INR, international normalised ratio; NAR, non-anatomic resection; NBNC, non-HBV non-hepatitis C virus; PT, prothrombin time; TACE, transcatheter arterial chemoembolisation.