Figure 2.

Mutational profile of EGFR NSCLC to neuroendocrine-transformed patients with multiple time points. NGS mutation results from both tissue and liquid biopsy were classified according to mutation subtypes, including EGFR exon 19 deletion; exon 19 deletion and amplification; exon 19 deletion, amplification, and T790M; L858R; L861Q and amplification; and other mutational subtypes, including substitution; amplification; deletion; fusion; splice site; loss; frameshift; rearrangement. The time points of the different molecular testing results are denoted by letters A-I for each patient in sequential order that they were performed.