TABLE 3.
Distribution of msrA, linA/linA′, vga, vgb, vat, and vatB resistance genes among staphylococcal isolatesa
| Gene |
S. aureus(n = 144)
|
Coagulase-negative staphylococci (n = 150)
|
|||
|---|---|---|---|---|---|
| No. (%) | Resistance phenotype | No. (%) | Resistance phenotype | Species (no.) | |
| msrA | 3 (2.1) | MSSA or MRSA, M | 17 (11.3) | MSCNS, M | S. epidermidis (2) |
| MRCNS, M | S. epidermidis (1) | ||||
| MRCNS, M | S. haemolyticus (10) | ||||
| MSCNS, M | S. saprophyticus (2) | ||||
| MSCNS, M | S. hominis (2) | ||||
| msrA + ermA | 3 (2.0) | MSCNS, MLS inducible | S. hominis (1) | ||
| MRCNS, MLS inducible | S. haemolyticus (2) | ||||
| msrA + ermC | 2 (1.3) | MRCNS, MLS constitutive | S. haemolyticus (1) | ||
| MSCNS, MLS inducible | S. hominis (1) | ||||
| linA/linA′ | 2 (1.3) | MRCNS, L | S. epidermidis (2) | ||
| linA/linA′ + msrA | 2 (1.3) | MRCNS, M, L | S. epidermidis (1) | ||
| MRCNS, M, L | S. haemolyticus (1) | ||||
| linA/linA′ + ermA | 1 (0.7) | MSCNS, L | S. hominis (1) | ||
| linA/linA′ + ermC | 1 (0.7) | MSSA, MS inducible, L constitutive | 1 (0.7) | MRCNS, MS inducible, L constitutive | S. epidermidis (1) |
| linA/linA′ + ermB + ermC | 1 (0.7) | MRCNS, MS inducible, L constitutive | S. haemolyticus (1) | ||
| vga | 3 (2.0) | MRCNS, SgA | S. epidermidis (2) | ||
| MRCNS, SgA, L | S. haemolyticus (1) | ||||
| vga + ermA | 8 (5.3) | MRCNS, MLS constitutive, SgA | S. epidermidis (6) | ||
| MRCNS, MLS constitutive, SgA | S. haemolyticus (1) | ||||
| MSCNS, MLS inducible | S. epidermidis (1) | ||||
| vga + ermA + ermC | 1 (0.7) | MRCNS, MLS constitutive, SgA | S. epidermidis (1) | ||
| vga + vgb + vat + ermA | 1 (0.7) | MRCNS, MLS constitutive, SgA, Pr, QD | S. epidermidis (1) | ||
| vatB + ermA | 10 (7.6) | MRSA, MLS constitutive, SgA, Pr, QD | |||
| 1 (0.7) | MRSA, MLS constitutive | ||||
| vatB + ermC | 2 (1.3) | MRCNS, MLS constitutive, SgA, Pr, QD | S. epidermidis (2) | ||
| No resistance gene | 1 (0.7) | MRSA, L, SgA | 4 (2.7) | MSCNS, L, SgA | S. sciuri (3) |
| MRCNS, L, SgA | S. sciuri (1) | ||||
| 1 (0.7) | MSCNS, M | S. saprophyticus (1) | |||
| 1 (0.7) | MRCNS, SgA | S. warneri (1) | |||
| 1 (0.7) | MSCNS, MLS constitutive | S. warneri (1) | |||
a
Abbreviations: M, macrolides; MSCNS, methicillin-susceptible coagulase-negative staphylococci; MRCNS, methicillin-resistant coagulase-negative staphylococci; L, lincosamides; MS, macrolides-streptogramin B; SgA, streptogramin A; Pr, pristinamycin; and QD, quinupristin-dalfopristin.