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. 2022 Mar 3;23(5):2799. doi: 10.3390/ijms23052799
FVC forced volume capacity
COPD chronic obstructive pulmonary disease
CO carbon monoxide
NOx nitrogen oxides
SO2 sulfur dioxide
IPA polycyclic aromatic hydrocarbons
PM particulate matter
VOC volatile organic compounds
COHb carboxyhemoglobin
NO2 nitrogen dioxide
B[a]P benzo-[a]-pyrene
IARC International Agency for Research on Cancer
ESCAPE European study of cohorts for air pollution effects
SIN sites of national interest
CISAS International Center for Advanced Studies in Environment, Ecosystem and Human Health
OMS World Health Organization
POP persistent organic pollutants
PCB polychlorinated biphenyls
PBDE polybrominated diphenyl ethers
EFSA European Food Safety Authority
TLR4/NF-kB Toll-like receptor 4/nuclear factor kappa-light-chain-enhancer of activated B cells
UE European Union
AM alveolar macrophages
TNF-α tumor necrosis factor
IL- interleukin-
DAMP damage-associated molecular pattern
GM-CSF granulocyte-macrophage colony-stimulating factor
MCP-1 monocyte chemoattractant protein 1
TSLP timic stromal lymphopoietin
O3 ozone
C6H6 benzene
As arsenic
Cd cadmium
Ni nickel
ROS reactive oxygen species
DUOX1 duox ossidasi 1
NADPH nicotinamide adenine dinucleotide phosphate
Nrf2 erythroid 2-like 2
ALI air–liquid interface
LOC lung-on-a-chip
IPSC induced pluripotent stem cells
NP nanoparticles
TEER transepithelial electrical resistance
NAC N-acetyl cysteine
Hg mercury
COX-2 cyclooxygenase-2
RNA ribonucleic acid
mRNA messenger RNA
Zonula Occludens-1 ZO-1