Table 1.

Associations between maternal body composition and HMO concentrations.

Maternal Predictor	Secretor			Non-Secretor			Interaction
	Parameter Estimate	SE	p-Value	Parameter Estimate	SE	p-Value	p-Value
	2′FL
FM (%)	0.43	0.16	0.01	0.07	0.03	0.01	0.03
Log (FMI (kg/m2))	6.05	3.00	0.05	1.25	0.53	0.02	0.23
Log (FM/FFM)	7.85	4.11	0.06	1.59	0.61	0.01	0.14
	3′SL
Log (FM (kg))	−0.34	1.48	0.82	−7.13	3.03	0.02	0.05
FM (%)	−0.04	0.08	0.66	−0.37	0.12	<0.001	0.02
Log (FMI (kg/m2))	−0.63	1.53	0.68	−5.88	2.56	0.03	0.08
Log (FM/FFM)	−2.81	2.04	0.17	−8.36	2.68	<0.001	0.11
	FLNH
Age	−0.12	0.24	0.63	1.80	0.69	0.01	0.01
Log (Weight (kg))	14.32	5.43	0.01	−36.11	22.83	0.12	0.04
Log (BMI (kg/m2))	13.81	5.99	0.03	−15.11	15.95	0.35	0.10
Log (FM (kg))	8.37	3.35	0.02	−16.06	8.88	0.08	0.01
Log (FMI (kg/m2))	7.86	3.50	0.03	−11.22	7.82	0.16	0.03
	Entire cohort
	2′FL
Log (Weight (kg))	3.63	1.52	0.02	-	-	-	-
Log (BMI (kg/m2))	2.37	1.04	0.03	-	-	-	-
Log (FM (kg))	1.68	0.61	0.01	-	-	-	-
	Log (LNH)
Log (BMI (kg/m2))	0.73	0.27	0.01	-	-	-	-
FFMI (kg/m2)	0.05	0.02	0.02	-	-	-	-

Data are parameter value ± standard error of measurement (SE). When the interaction term with secretor status was present in the final model, results were broken down by secretor and non-secretor groups, whereas when the interaction term was not present in the final model, results are presented for the entire cohort. Significant p-values are indicated by bold text. 2′FL—2′-fucosyllactose; 3′SL—3′-sialyllactose; BMI—body mass index; FFMI—fat-free mass index; FLNH—fucosyllacto-N-hexaose; FM—fat mass; FM/FFM—fat mass to fat-free mass ratio; FMI—fat mass index; LNH—lacto-N-hexaose.