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. 2022 Mar 5;23(5):2865. doi: 10.3390/ijms23052865

Table 2.

Associations between maternal body composition and human milk bacterial OTU relative abundance.

Maternal Predictor Secretor Non-Secretor Interaction
Parameter Estimate SE p-Value Parameter Estimate SE p-Value p-Value
OTU03 (Streptococcus salivarius)
Log (Weight (kg)) −2.24 0.82 0.01 6.01 5.07 0.24 0.12
Log (BMI (kg/m2)) −2.52 0.89 0.01 4.44 2.8 0.12 0.02
Log (FM (kg)) −1.37 0.5 0.01 2.63 2 0.19 0.06
FM (%) −0.06 0.03 0.04 0.12 0.08 0.17 0.05
Log (FMI (kg/m2)) −1.42 0.52 0.01 2.25 1.51 0.14 0.02
Log (FM/FFM) −1.33 0.64 0.04 2.66 1.96 0.18 0.06
OTU06 (Streptococcus lactarius)
Age 0.03 0.04 0.41 0.82 0.26 <0.001 <0.001
OTU08 (Gemella haemolysans)
Log (BMI (kg/m2)) −0.69 1.28 0.59 5.43 2.39 0.03 0.03
FFMI (kg/m2) −0.05 0.11 0.64 0.55 0.24 0.03 0.03
Log (FMI (kg/m2)) −0.37 0.74 0.62 2.62 1.22 0.04 0.04
OTU10 (Veillonella nakazawae)
FFMI (kg/m2) 0.12 0.06 0.04 0.42 0.19 0.03 0.14
Entire cohort
OUT01 (Streptococcus mitis)
Age 0.07 0.03 0.04 - - - -
OTU02 (Staphylococcus epidermidis)
Log (Weight (kg)) −1.54 0.69 0.03 - - - -
FFM (kg) −0.04 0.02 0.02 - - - -
Log (FM (kg)) −1.04 0.43 0.02 - - - -
Log (FMI (kg/m2)) −0.9 0.43 0.04 - - - -
OTU10 (Veillonella nakazawae)
FFM (kg) 0.04 0.02 0.03 - - - -

Data are parameter value ± standard error of measurement (SE); note that these estimates are on the logit scale. When the interaction term with secretor status was present in the final model, results were separated by secretor and non-secretor groups, whereas when the interaction term was not present in the final model, results were presented for the entire cohort. Significant p-values are indicated by the bold text. BMI—body mass index; ECS—emergency caesarean section; FFM—fat-free mass; FFMI—fat-free mass index; FM—fat mass; FM/FFM—fat mass to fat-free mass ratio; FMI—fat mass index; MOD—mode of delivery.