Table 5.
Associations between bacterial OTUs and infant body composition at three months postpartum.
| Human Milk OTUs | Secretor | Non-Secretor | Interaction | Log (Infant Milk Intake) | ||||
|---|---|---|---|---|---|---|---|---|
| Parameter Value | SE | p-Value | Parameter Value | SE | p-Value | p-Value | p-Value | |
| Head circumference (cm) | ||||||||
| OTU01 (Streptococcus mitis) | 0.01 | 0.01 | 0.56 | −0.03 | 0.01 | 0.01 | 0.03 | 0.03 |
| Length-for-age z-score | ||||||||
| OTU01 (Streptococcus mitis) | −0.00 | 0.01 | 0.61 | −0.02 | 0.01 | 0.03 | 0.15 | 0.03 |
| BMI-for-age z-score | ||||||||
| OTU05 (Streptococcus parasanguis) | −0.02 | 0.02 | 0.42 | 0.01 | 0.01 | 0.02 | 0.16 | 0.03 |
| Head circumference-for-age z-score | ||||||||
| OTU01 (Streptococcus mitis) | 0.00 | 0.01 | 0.63 | −0.03 | 0.01 | <0.001 | 0.01 | 0.10 |
| Entire cohort | ||||||||
| Weight (kg) | ||||||||
| OTU05 (Streptococcus parasanguis) | 0.02 | 0.01 | <0.001 | - | - | - | - | <0.001 |
| Length (cm) | ||||||||
| OTU02 (Staphylococcus epidermidis) | −0.04 | 0.02 | 0.04 | - | - | - | - | <0.001 |
| Weight-for-length z-score | ||||||||
| OTU02 (Staphylococcus epidermidis) | 0.02 | 0.01 | 0.02 | - | - | - | - | NA |
| OTU06 (Streptococcus lactarius) | 0.02 | 0.01 | 0.04 | - | - | - | - | NA |
| Weight-for-age z-score | ||||||||
| OTU05 (Streptococcus parasanguis) | 0.01 | 0.01 | 0.03 | - | - | - | - | <0.001 |
| BMI-for-age z-score | ||||||||
| OTU06 (Streptococcus lactarius) | 0.02 | 0.01 | 0.01 | - | - | - | - | NA |
| Log fat-free mass (kg) | ||||||||
| OTU05 (Streptococcus parasanguis) | 0.00 | 0.00 | <0.001 | - | - | - | - | <0.001 |
| Log fat-free mass index (kg/m2) | ||||||||
| OTU05 (Streptococcus parasanguis) | 0.00 | 0.00 | 0.01 | - | - | - | - | <0.001 |
| Fat mass (kg) | ||||||||
| OTU05 (Streptococcus parasanguis) | 0.01 | 0.00 | 0.03 | - | - | - | - | <0.001 |
| OTU06 (Streptococcus lactarius) | 0.01 | 0.00 | 0.03 | - | - | - | - | 0.01 |
| Fat mass index (kg/m2) | ||||||||
| OTU05 (Streptococcus parasanguis) | 0.01 | 0.01 | 0.03 | - | - | - | - | <0.001 |
| OTU06 (Streptococcus lactarius) | 0.02 | 0.01 | 0.02 | - | - | - | - | 0.03 |
| Fat mass (%) | ||||||||
| OTU06 (Streptococcus lactarius) | 0.05 | 0.03 | 0.04 | - | - | - | - | NA |
| Fat mass to fat-free mass ratio | ||||||||
| OTU06 (Streptococcus lactarius) | 0.00 | 0.00 | 0.03 | - | - | - | - | NA |
Data are parameter estimate ± standard error of measurement (SE); note that these estimates are on the logit scale. When the interaction term with secretor status was present in the final model, results were separated by secretor and non-secretor groups, whereas when the interaction term was not present in the final model, results were presented for the entire cohort. Significant p-values are indicated by the bold text.