Table 4.
Fast Metabolizers n = 58 | Slow Metabolizers n = 22 | p-Value | |
---|---|---|---|
CMV infection | |||
before switch to LCPT | 8 (13.8%) | 2 (9.1%) | 0.719 |
after switch to LCPT (3 y-follow up) | 3 (5.2%) | 2 (9.1%) | 0.612 |
BKV infection | |||
before switch to LCPT | 3 (5.2%) | 3 (13.6%) | 0.338 |
after switch to LCPT (3 y-follow up) | 1 (1.7%) | 0 | 1 |
BKV nephropathy | |||
before switch to LCPT | 1 (1.7%) | 2 (9.1%) | 0.182 |
after switch to LCPT (3 y-follow up) | 0 | 0 | - |
CNIT | |||
before switch to LCPT | 3 (5.2%) | 2 (9.1%) | 0.612 |
after switch to LCPT (3 y-follow up) | 1 (1.7%) | 0 | 1 |
acute rejection | |||
before switch to LCPT | 12 (20.7%) | 9 (40.9%) | 0.089 |
after switch to LCPT (3 y-follow up) | 8 (13.8%) | 2 (9.1%) | 0.719 |
death within 3 years after switch | 2 (3.4%) | 0 | 1 |
diabetes mellitus | |||
before switch to LCPT | 1 (1.7%) | 1 (4.5%) | 0.477 |
after switch to LCPT (3 y-follow up) | 0 | 0 | - |
CMV, cytomegalovirus; BKV, BK-virus; CNIT, calcineurin-inhibitor nephrotoxicity; LCPT, LCP-tacrolimus. p-values are from the Fisher’s exact test.