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. 2022 Feb 26;11(5):1290. doi: 10.3390/jcm11051290

Table 4.

Complications before and after switch.

Fast Metabolizers n = 58 Slow Metabolizers n = 22 p-Value
CMV infection
before switch to LCPT 8 (13.8%) 2 (9.1%) 0.719
after switch to LCPT (3 y-follow up) 3 (5.2%) 2 (9.1%) 0.612
BKV infection
before switch to LCPT 3 (5.2%) 3 (13.6%) 0.338
after switch to LCPT (3 y-follow up) 1 (1.7%) 0 1
BKV nephropathy
before switch to LCPT 1 (1.7%) 2 (9.1%) 0.182
after switch to LCPT (3 y-follow up) 0 0 -
CNIT
before switch to LCPT 3 (5.2%) 2 (9.1%) 0.612
after switch to LCPT (3 y-follow up) 1 (1.7%) 0 1
acute rejection
before switch to LCPT 12 (20.7%) 9 (40.9%) 0.089
after switch to LCPT (3 y-follow up) 8 (13.8%) 2 (9.1%) 0.719
death within 3 years after switch 2 (3.4%) 0 1
diabetes mellitus
before switch to LCPT 1 (1.7%) 1 (4.5%) 0.477
after switch to LCPT (3 y-follow up) 0 0 -

CMV, cytomegalovirus; BKV, BK-virus; CNIT, calcineurin-inhibitor nephrotoxicity; LCPT, LCP-tacrolimus. p-values are from the Fisher’s exact test.