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. 2022 Mar 5;23(5):2844. doi: 10.3390/ijms23052844

Table 1.

Orthologues of T. b. brucei drug transporters, showing % identity by amino acid sequence.

Species Gene ID T. brucei
AT1
Tb927.5.286b
T. evansi AGT37292.1 99.35
T. equiperdum SCU70586.1 99.78
T. congolense - <75
AQP2
Tb927.10.14170
T. evansi TevSTIB805.10.14910 100
T. equiperdum not annotated 100 1
T. congolense - <75
MFST
Tb927.9.6360 2 Tb927.9.6370 Tb927.9.6380
T. evansi TevSTIB805.9.4540 99.58 89.15 96.87
TevSTIB805.9.4550 89.79 98.30 90.43
TevSTIB805.9.4560 96.24 88.72 98.96
T. equiperdum RHW70022.1 96.24 88.72 98.96
RHW70658.1 88.30 97.23 90.21
RHW70215.1 96.45 88.94 99.16
T. congolense - <75 <75 <75

1 P. Buscher and N. van Reet, personal communication; 2 Gene ID identified by Alsford et al. [28] as being associated with suramin resistance after RNAi knockdown.