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. 2022 Mar 3;23(5):2798. doi: 10.3390/ijms23052798

Figure 2.

Figure 2

Effect of the NO-donor SNP on the outward current of rat tail artery smooth muscle cells in the presence of the NO-scavenger hydroxocobalamin. (a) Example of the time course of the effect of SNP in the presence of 1 mM hydroxocobalamin (NO scav) on the outward current. The application period is shown as grey area; start of application is marked as (s), end of application as (e). The current was elicited with use of a 500 ms-long voltage step from a holding potential of −40 mV to a test potential of +70 mV. (b) Examples of traces of the outward current elicited with use of a 500 ms-long voltage step from a holding potential of −40 mV to a test potential of +70 mV at the start (s) and at the end (e) of the application of SNP in the presence of 1 mM hydroxocobalamin. (c) Examples of current–voltage (I–MP) relationships of outward current elicited with use of a 1.5 s-long voltage ramp from a holding potential of −40 mV in the voltage range from −70 to +100 mV at the start (s) and at the end (e) of the application of SNP in the presence of 1 mM hydroxocobalamin.