Table 2.

Articles in the systematic review on emerging microorganisms in urethritis.

Article	Age-Sex	Predisposing Factors	Microorganism	Clinical Manifestations	Clinical Sample	Treatment	Microbiological Identification Method
Gregory JE et al., 1979	27-Male	Alcohol abuse	Neisseria meningitidis	Urethritis	Urethral exudate	Procaine penicillin Probenecid	Not described
Karolus JJ et al., 1980	29-Male	Oral-genital and vaginal contact	Neisseria meningitidis	Urethritis	Urethral exudate	Procaine penicillin	Not described
Chowdhury MNH et al., 1984	35-Male	Sexual relations with female partner (non- extramarital, oral-genital, or anal)	Streptococcus group B	Urethritis	Urethral exudate	Phenoxymethylpenicillin	Not described
Noble RC et al., 1985	25-Male	Vaginal and oral sexual relation with a female	Streptococcus pneumoniae	Urethritis	Urethral exudate	Ampicillin Probenecid	Not described
Hay PE et al., 1989	16-Male	Oral sex (female)	Neisseria meningitidis	Urethritis	Urethral exudate	Spectinomycin Doxycycline	Not described
Wilson APR et al., 1989	18-Male	Sexual relations with steady partner (female)	Neisseria meningitidis	Urethritis	Urethral exudate	Ampicillin Probenecid	Not described
Phillips EA et al., 1989	19-Male	Sexual contact (female)	Neisseria meningitidis	Urethritis	Urethral exudate	Amoxicillin Doxycycline	Not described
Shanmugaratnam K et al., 1989	25-Male	Oral-genital contact	Neisseria meningitidis	Urethritis	Urethral exudate	Ciprofloxacin	Not described
Faigel HC et al., 1990	20-Male	Oral-genital contact (female)	Neisseria meningitidis	Urethritis	Urethral exudate	Not described	Not described
Coker DM et al., 1991	36-Male	Sporadic sexual relations (female)	Moraxella urethralis	Urethritis	Urethral exudate	Ciprofloxacin	Not described
Quarto M et al., 1991	35-Male	Occasional oral sex with a female	Neisseria meningitidis	Urethritis	Urethral exudate	Ampicillin	Not described
Kanemitsu N et al., 2003	48-Male	Oral-genital contact	Neisseria meningitidis	Urethritis	Urethral exudate	Levofloxacin	Enzymatic profiles
Orden B et al., 2004	36-Male	Unprotected oral and vaginal sexual relations	Neisseria meningitidis	Urethritis	Urethral exudate	Ceftriaxone Doxycycline	API NH (bioMérieux)
Rodríguez CN et al., 2005	27-Male	Oral and vaginal sexual relations with several women	Neisseria meningitidis	Urethritis	Urethral exudate	Ceftriaxone Doxycycline	API NH (bioMérieux)
Urra E et al., 2005	38-Male	Sexual relations with steady partner (female)	Neisseria meningitidis	Urethritis	Urethral exudate	Minocycline	API NH (bioMérieux)
Abdolrasouli A et al., 2007	23-Male	Unprotected fellatio	Moraxella catarrhalis	Urethritis	Urethral and throat exudate	Ciprofloxacin	Not described
Koroglu M et al., 2007	43-Male	Multiple sexual partners	Streptococcus pneumoniae	Urethritis	Urethral exudate	Amoxicillin	BD BBL Crystal test
Galán-Sánchez F et al., 2011	18-Male	Sexual relations with multiple partners	Corynebacterium glucuronolyticum	Urethritis	Urethral exudate	Ciprofloxacin	API Coryne sistem
Katz AR et al., 2011	26-Male	Oral and vaginal sex with one woman	Neisseria meningitidis	Urethritis	Urethral exudate	Cefixime Azithromycin	API NH (bioMérieux)
Bousquet A et al., 2012	35-Male	Unprotected oral-genital sex with males and females	Neisseria meningitidis	Urethritis	Urethral exudate	Ceftriaxone Azithromycin	MALDI-TOF
Abdolrasouli A et al., 2013	27-Male	Possible unprotected sexual relations	Corynebacterium propinquum	Urethritis	Urethral exudate	Azithromycin Vancomycin	API Coryne system (bioMérieux)
Babics A et al., 2015	36-Male	Not described	Gardnerella vaginalis	Urethritis	Urine Blood	Azithromycin Ceftriaxone	MALDI-TOF (Bruker)
Gherardi G et al., 2015	37-Male	Not described	Corynebacterium glucuronolyticum	Genitourinary tract infection	Urethral exudate Semen Urine	Ciprofloxacin	MALDI-TOF RNAr 16S gene sequencing
Seynabou Lo et al., 2015	52-Male	Previous urethroplasties	Corynebacterium aurimucosum	Urinary tract infection	Urine	Imipenem	MALDI-TOF
Grandolfo M et al., 2016	39-Male	Not described	Neisseria elongata nitroreducens	Purulent balanoposthitis Urethritis	Urethral exudate	Ceftriaxone Topical mupirocin	Vitek 2 compact system (bioMérieux)
Jannic A et al., 2019	22-Male	Sexual relations with steady partner (female)	Neisseria meningitidis	Urethritis	Urethral exudate	Ceftriaxone Azithromycin	MALDI-TOF